PRCISR™ CRISPR
Vivlion’s CRISPR-enabled Discovery Platform
Technology
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PRCISR™ CRISPR plasmids come in three gRNA arrangements: single, fixed-pair and dual-multiplex. Each plasmid is available as an all-in-one system containing the nuclease, and is fully customizable to meet your specific research needs.
Customize your plasmids with options for promoter choice, tracrRNA, antibiotic selection marker, fluorescence, barcode and scRNA-seq capture sequence.
Our libraries are designed to address various challenges in CRISPR screening, catering to applications that utilize sparse cell material, high-volume screens and large combinatorial experiments.
Partner with Vivlion to enhance your CRISPR screening capabilities with our advanced library solutions.
PRCISR™ CRISPR gRNA libraries
Available in both single and dual-combinatorial formats, our PRCISR™ CRISPR gRNA libraries offer comprehensive coverage. Choose from a selection of genome-wide and protein family-focused libraries, or customize a library to meet your specific research needs. For those conducting in-house screening experiments, our libraries are delivered ready for lentiviral transduction, together with all necessary protocols for planning and executing your CRISPR screen.
PRCISR™ CRISPR screening
Prefer to outsource your screening projects? Our fully integrated CRISPR discovery platform covers every step of the process, from experimental planning to bioinformatic analysis. Let us handle the details, ensuring a seamless and efficient workflow.
Innovative 3Cs technology
Experience the unique benefits of our innovative, patent-protected 3Cs technology, which guarantees superior uniformity, diversity and efficiency in your CRISPR experiments.
Partner with us to unlock the full potential of your research with our state-of-the-art CRISPR solutions.
Link to our proprietary PRCISR technology
Superior library performance
Our libraries feature an exceptionally uniform distribution of gRNAs (skew < 3), ensuring complete coverage of target sites. Diversity will not impact on the quality of reagents and you can choose between single and dual-combinatorial formats. Diversity will not impact on the quality of reagents and you can choose between single and dual-combinatorial formats.
Large-scale screening services
We offer cutting-edge CRISPR screening as a full service. Benefit from our innovative platform and our comprehensive solution including bioinformatic analysis. We will guide you through the entire process from experimental planning to data anaylsis. We will guide you through the entire process from experimental planning to data anaylsis.
Explore the Vivlion® benefits
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Experimental strategy and design:Our dedicated team provides comprehensive support in planning your CRISPR experiments, ensuring optimal strategy implementation. |
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PCR-free uniform libraries: Our uniformly distributed PRCISRTM CRISPR libraries ensure that all your target genes are properly represented. |
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High gene editing efficiency: PRCISRTM CRISPR libraries maximize gene editing efficiency, resulting in >90% editing rates. |
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Limited cell material: PRCISRTM CRISPR libraries enable low experimental coverage, allowing the screening of limited cell material (e.g. iPS cells, primary). |
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Multigenetic exploration: Combinatorial PRCISRTM CRISPR solutions enable genetic interaction testing and target discovery at unprecedented scale. |
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Tailored services: We deliver screening and bioinformatic services, from experimental planning to sophisticated tools for data analysis & integration. |
Link to our proprietary PRCISR technology
“We are thrilled to work with Vivlion for their high-quality CRISPR libraries that have excellent guide representation. The superb quality of their products and technical support has made them a highly valued contributor. Vivlion’s genome-wide CRISPR libraries will enable us to continue discovering synthetic lethal drug targets with lower false negative rates, which will ultimately benefit cancer patients in need of new therapeutic options.”
Contact us
We would like to hear more about your CRISPR questions and applications – please reach out to us by completing the following form:
