Next-generation CRISPR screening


Next-generation CRISPR screening


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Vivlion is a spin-out of Goethe University Frankfurt, founded in December 2018 by a team of scientists together with the university as a shareholder. Seed funding was secured by a private equity company, gsccb Beteiligungsverwaltung GmbH. We provide innovative gene editing reagents and screening services for the global R&D market. Our success is based on the proprietary 3Cs technology developed at Goethe University’s Institute of Biochemistry II (IBC2).


Manuel Kaulich - Vivlion

Manuel Kaulich

Chief Scientific Officer & Co-Founder

Manuel is one of the co-founders of Vivlion and a Goethe University Professor, heading the functional genomics and genetic vulnerabilities group at the Institute of Biochemistry II. His laboratory developed the 3Cs technology and dissects unperturbed and malignant cell cycle entry regulation. Manuel studied biotechnology/molecular life science, obtained his PhD at the MPI of Biochemistry and the Biozentrum in Basel and then moved to University of California San Diego for his postdoctoral studies. Since then, he became an expert in gene editing applying CRISPR and rAAVs in functional genetic screens.  


Martin Wegner - Vivlion

Martin Wegner

Head of R&D and Customer Solutions

Martin was trained as bioinformatician at Goethe University and is one of the inventors of the 3Cs technology. He is an expert in CRISPR screening and analysis, including combinatorial applications to identify genetic interactions. Following his PhD in the Kaulich laboratory, he joined the Vivlion team, heading the R&D and customer solutions section, focusing especially on Vivlion’s proprietary bioinformatic pipeline for experimental design and analysis. Martin’s research interests evolved from network biology and its applications to the analysis of neurodegenerative diseases towards dissecting genetic vulnerabilities using sophisticated CRISPR technologies. 

Elena Vialetto -

Elena Vialetto

Scientific Project Manager

Elena studied biotechnology and obtained a master’s degree from the University of Padova. During her PhD in the Beisel laboratory at Helmholtz Institute in Würzburg, she deciphered the collateral activity of Cas13 in bacteria, tested the efficacy of different CRISPR systems as antimicrobials and investigated the influence of gRNA secondary structure on targeting. With her expertise in various CRISPR systems, genetic engineering and genome editing, she supports Vivlion’s customers in experimental planning and is responsible for managing scientific projects tailored to customer needs.

Elena Vialetto -

Angela Hinchie

Scientific Project Manager

Angela completed her PhD in Molecular Pharmacology in the Alder laboratory at the University of Pittsburgh. During her PhD she focused on the design and application of molecular tools to study telomere extension and has extensive experience with molecular cloning, gene editing and mammalian cell culture. Her work culminated in the conduction of a CRISPR screen identifying telomere maintenance genes. As a Scientific Project Manager, Angela supports customers in the design and implementation of their individual CRISPR screening projects.

Ronay Çetin -

Ronay Çetin

Scientific Support Manager

Ronay was trained in molecular biology, genetics and bioengineering at Sabanci University (Istanbul) before starting a PhD in the Kaulich group at Goethe University Frankfurt. During his PhD, he has been utilizing the 3Cs CRISPR screening technology to understand the role of cellular communication in oncogene-mediated transformation. He is an expert in PRCISR CRISPR technologies and has specialized in combinatorial CRISPR screening with diverse Cas nucleases. Ronay recently joined Vivlion as a Scientific Support Manager.

Sönke Bästlein - Vivlion

Sönke Bästlein

Chief Financial Officer

Sönke spent more than 20 years in consulting at McKinsey & Company, Inc., and in private equity at Nordic Capital. He is angel investor and managing shareholder of private investment management firm gsccb Beteiligungsverwaltung GmbH. Sönke’s experience includes serving on advisory and supervisory boards, and he teaches “Equity Governance” at Goethe University Frankfurt / Main. He holds a diploma in mechanical engineering (specialising in process engineering) from RWTH Aachen and a PhD in business administration from Goethe University. Sönke joined the Vivlion team as investor in 2019 and as CFO end of 2022.  

Kerstin Koch - Vivlion

Kerstin Koch

Head of Business Development & Co-Founder

Kerstin is an experienced scientific manager who has a track record in strategically planning and coordinating large-scale, multidisciplinary research consortia, both at University of Cambridge (UK) and at Goethe University Frankfurt. Following her diplomas in biochemistry and journalism, she took a deep dive into pharma PR before obtaining a PhD in biochemistry from University of Hamburg. Kerstin is one of the founders of Vivlion and today responsible for business development. 

Claudio Sabatelli - Vivlion

Claudio Sabatelli

Operations Manager

Prior to joining Vivlion GmbH as an Operations Manager, Claudio spent three years in consulting private and listed companies on capital market topics. Claudio holds a masters degree in ecology and evolution from Goethe University Frankfurt and spent two years working for the Chinese Academy of Science in Chengdu. 


Ivan - Vivlion

Ivan Đikić

Chief Advisor & Co-Founder

Ivan is a leading expert in the fields of ubiquitin biology and autophagy. He is one of the founders of Vivlion and chief advisor to the company. He is Director of the Institute of Biochemistry II at Goethe University, where 3Cs technology was invented. In his research lab, a multidisciplinary team of scientists elucidates the molecular principles that drive human diseases such as cancer, neurodegeneration and infection. For his scientific accomplishments, Ivan received numerous awards, including the Ernst Jung Prize for Medicine and the Gottfried Wilhelm Leibniz Prize. In addition, he is a honorary member of the American Academy of Arts and Sciences. Ivan holds a PhD from University of Zagreb School of Medicine.

You – take your next career step at Vivlion

We are always looking for talents who are keen to join us. If you are interested in being part of the exciting journey of Vivlion, please forward your application with cover letter, CV, references in one pdf to


The CRISPR MEDICINE Conference 2024

23rd April 2024 – Conference
1st CRISPR Medicine Conference takes place from 23-25 April in Copenhagen, Denmark.
Meet the European CRISPR community, join  the Functional Genomics session co-organized by Vivlion & watch out for the announcement of Vivlion’s famous fun run!

The CRISPR MEDICINE Conference 2024

15th April 2024 – Interview by CRISPR MEDICINE News
Vivlion’s CSO Manuel Kaulich and Head of R&D Martin Wegner discuss with Karen O’Hanlon Cohrt challenges and opportunities in CRISPR screening. The interview provides a great educational resource for setting up CRISPR screens and highlights latest technological developments. Read online or download.

The CRISPR MEDICINE Conference 2024

8th January 2024 – News
Vivlion is organizing a session on functional genomics within CRISPR Medicine Conference 2024 in Copenhagen (23-25 April 2024).
Secure your space and take advantage of the early bird offer until 12th January.

CRISPR Würzburg logo

27th June 2023 – News
CRISPR 2023 Conference Würzburg: Join the fun run hosted by Vivlion!
Meet at 7 pm on 29th June.

Contact us

We would like to hear more about your CRISPR questions and applications – please reach out to us by completing the following form:

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